Stadium: University of Charleston Stadium Round: 1
| НКААФ | 2022/09/01 23:00 | Gannon University Golden Knights v University of Charleston Golden Eagles | L | 47-13 |
| НКААФ | 2022/11/12 17:00 | University of Charleston Golden Eagles v West Virginia State Yellow Jackets | L | 35-42 |
| НКААФ | 2022/11/05 16:00 | Wheeling Jesuit v University of Charleston Golden Eagles | W | 19-22 |
| НКААФ | 2022/10/29 18:00 | W. Virginia Bobcats v University of Charleston Golden Eagles | W | 0-44 |
| НКААФ | 2022/10/22 16:00 | University of Charleston Golden Eagles v Unc Pembroke Braves | W | 70-21 |
| НКААФ | 2022/10/15 16:00 | Concord University Mountain Lions v University of Charleston Golden Eagles | L | 68-60 |
| НКААФ | 2022/10/08 16:00 | University of Charleston Golden Eagles v Glenville State Pioneers | W | 41-34 |
| НКААФ | 2022/10/01 16:00 | Notre Dame Falcons v University of Charleston Golden Eagles | L | 49-24 |
| НКААФ | 2022/09/24 17:00 | University of Charleston Golden Eagles v Alderson Broaddus Battlers | W | 62-7 |
| НКААФ | 2022/11/12 17:00 | Gannon University Golden Knights v Shippensburg Raiders | L | 28-35 |
| НКААФ | 2022/11/05 16:00 | California Vulcans v Gannon University Golden Knights | W | 13-25 |
| НКААФ | 2022/10/29 16:00 | Gannon University Golden Knights v Iup Crimson Hawks | W | 43-36 |
| НКААФ | 2022/10/22 16:00 | Gannon University Golden Knights v Mercyhurst Lakers | W | 49-14 |
| НКААФ | 2022/10/15 17:00 | Σλιπερι Ροκ v Gannon University Golden Knights | L | 40-14 |
| НКААФ | 2022/10/08 18:00 | Edinboro Fighting Scots v Gannon University Golden Knights | W | 17-35 |
| НКААФ | 2022/10/01 16:00 | Gannon University Golden Knights v Seton Hill Griffins | W | 21-10 |
| НКААФ | 2022/09/24 17:00 | Clarion Golden Eagles v Gannon University Golden Knights | W | 24-47 |